Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530427 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10PRNP | |
| SCHEMBL8529950 | 0.82 | PRNP (0.40) | ALDH1A1PRNPRXFP1KMT2AMAPT | |
| SCHEMBL8764852 | 0.80 | PRNP (0.57) | ALDH1A1HPGDKDM4EPRNPRXFP1 | |
| SCHEMBL8797019 | 0.78 | LTC4S (0.39) | ALDH1A1HPGDPRNPRXFP1TNF | |
| SCHEMBL28702281 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4ETP53HTT | |
| SCHEMBL7244423 | 0.71 | ALDH1A1 (0.36) | ALDH1A1HPGDKDM4ETP53HTT | |
| SCHEMBL7050190 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4ETP53HTT | |
| SCHEMBL8528852 | 0.70 | L3MBTL1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10PRNP | |
| SCHEMBL8528294 | 0.69 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4ETP53HTT | |
| SCHEMBL7437234 | 0.69 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4ETP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |