Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796956 | 0.93 | CHRNA7 (0.49) | CHRNA7FKBP1AL3MBTL1CACNA1BALDH1A1 | |
| SCHEMBL8797726 | 0.89 | CHRNA7 (0.48) | CHRNA7FKBP1AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8797447 | 0.87 | CHRNA7 (0.46) | CHRNA7FKBP1AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8796974 | 0.86 | CHRNA7 (0.45) | CHRNA7L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL8655149 | 0.86 | CHRNA7 (0.47) | CHRNA7FKBP1AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8797271 | 0.85 | CHRNA7 (0.47) | CHRNA7FKBP1AL3MBTL1 | |
| SCHEMBL8798365 | 0.85 | CHRNA7 (0.44) | CHRNA7FKBP1AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8797402 | 0.84 | CHRNA7 (0.53) | CHRNA7FKBP1ACACNA1BTBXAS1 | |
| SCHEMBL8797472 | 0.83 | CHRNA7 (0.47) | CHRNA7FKBP1AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8796913 | 0.83 | CHRNA7 (0.52) | CHRNA7FKBP1ACACNA1BALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |