Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798365 | 0.92 | CHRNA7 (0.44) | CHRNA7FKBP1AL3MBTL1KDM4EMEN1 | |
| SCHEMBL8797271 | 0.91 | CHRNA7 (0.47) | CHRNA7FKBP1AL3MBTL1LMNAMTOR | |
| SCHEMBL8797726 | 0.90 | CHRNA7 (0.48) | CHRNA7FKBP1AL3MBTL1KDM4EMEN1 | |
| SCHEMBL8796974 | 0.87 | CHRNA7 (0.45) | CHRNA7L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8655149 | 0.87 | CHRNA7 (0.47) | CHRNA7FKBP1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8797115 | 0.87 | CHRNA7 (0.50) | CHRNA7FKBP1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8796852 | 0.86 | L3MBTL1 (0.45) | CHRNA7FKBP1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8796956 | 0.86 | CHRNA7 (0.49) | CHRNA7FKBP1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8797472 | 0.84 | CHRNA7 (0.47) | CHRNA7FKBP1AL3MBTL1KDM4EMEN1 | |
| SCHEMBL8797176 | 0.83 | LMNA (0.52) | CHRNA7FKBP1AL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |