Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796852 | 0.93 | L3MBTL1 (0.45) | CHRNA7L3MBTL1FKBP1ALMNAMTOR | |
| SCHEMBL8797447 | 0.91 | CHRNA7 (0.46) | CHRNA7L3MBTL1FKBP1ALMNAMTOR | |
| SCHEMBL8797726 | 0.89 | CHRNA7 (0.48) | CHRNA7L3MBTL1FKBP1A | |
| SCHEMBL8798365 | 0.87 | CHRNA7 (0.44) | CHRNA7L3MBTL1FKBP1ALMNAMTOR | |
| SCHEMBL8796974 | 0.86 | CHRNA7 (0.45) | CHRNA7L3MBTL1LMNATDP1 | |
| SCHEMBL8655149 | 0.85 | CHRNA7 (0.47) | CHRNA7FKBP1ATDP1MAPT | |
| SCHEMBL8797115 | 0.85 | CHRNA7 (0.50) | CHRNA7L3MBTL1FKBP1A | |
| SCHEMBL8796956 | 0.85 | CHRNA7 (0.49) | CHRNA7L3MBTL1FKBP1A | |
| SCHEMBL8797176 | 0.84 | LMNA (0.52) | CHRNA7L3MBTL1FKBP1ALMNAMTOR | |
| SCHEMBL8797141 | 0.83 | L3MBTL1 (0.49) | CHRNA7L3MBTL1FKBP1ALMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |
| EP-0754184-A1 | CEPHALOSPORIN ANTIBIOTICS | Microcide Pharmaceuticals, Inc. (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1995026966-A1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |