Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797726 | 0.96 | CHRNA7 (0.48) | CHRNA7FKBP1AALDH1A1KDM4EHPGD | |
| SCHEMBL8796974 | 0.93 | CHRNA7 (0.45) | CHRNA7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8797447 | 0.87 | CHRNA7 (0.46) | CHRNA7FKBP1AALDH1A1KDM4EHPGD | |
| SCHEMBL8797115 | 0.86 | CHRNA7 (0.50) | CHRNA7FKBP1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8797271 | 0.85 | CHRNA7 (0.47) | CHRNA7FKBP1AMAPTTDP1 | |
| SCHEMBL8798365 | 0.85 | CHRNA7 (0.44) | CHRNA7FKBP1AALDH1A1KDM4EHPGD | |
| SCHEMBL8796956 | 0.85 | CHRNA7 (0.49) | CHRNA7FKBP1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10758726 | 0.84 | CHRNA7 (0.50) | CHRNA7FKBP1AALDH1A1KDM4EHPGD | |
| SCHEMBL8797472 | 0.83 | CHRNA7 (0.47) | CHRNA7FKBP1AALDH1A1KDM4EHPGD | |
| SCHEMBL8796852 | 0.81 | L3MBTL1 (0.45) | CHRNA7FKBP1AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843950-A | 1,4-dihydropyridine compound and pharmaceutical composition containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0801065-A1 | 1,4-DIHYDROPYRIDINE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1997-10-15 | — | — | EP | disclosed |