Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797357 | 0.85 | HRH3 (0.38) | HRH3FFAR1USP2KDM4CKDM4A | |
| SCHEMBL8797183 | 0.85 | PPARG (0.49) | HRH3FFAR1PPARG | |
| SCHEMBL8796972 | 0.76 | HRH3 (0.37) | HRH3FFAR1USP2KDM4CKDM4A | |
| SCHEMBL8798492 | 0.76 | HRH3 (0.38) | HRH3FFAR1USP2KDM4CKDM4A | |
| SCHEMBL6953755 | 0.76 | HRH3 (0.40) | HRH3FFAR1PPARG | |
| SCHEMBL9143100 | 0.75 | HPGD (0.54) | KMT2AHRH3FFAR1POLBL3MBTL1 | |
| SCHEMBL8798105 | 0.73 | HRH3 (0.44) | HRH3FFAR1USP2KDM4CKDM4A | |
| SCHEMBL9326656 | 0.73 | HRH3 (0.48) | KMT2AHRH3FFAR1KDM4CPPARG | |
| SCHEMBL8576970 | 0.72 | TSHR (0.36) | KMT2AFFAR1TSHRKDM4EALDH1A1 | |
| SCHEMBL8796899 | 0.71 | GAA (0.38) | KMT2AHRH3USP2KDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |