Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797185 | 0.85 | KMT2A (0.36) | HRH3PPARGFFAR1PDE6DUSP2 | |
| SCHEMBL8797348 | 0.82 | PPARG (0.56) | HRH3PPARGFFAR1HPGDHSD17B10 | |
| SCHEMBL8798492 | 0.82 | HRH3 (0.38) | HRH3RAB9APPARGFFAR1PDE6D | |
| SCHEMBL8796972 | 0.81 | HRH3 (0.37) | HRH3RAB9APPARGFFAR1HPGD | |
| SCHEMBL6953755 | 0.80 | HRH3 (0.40) | HRH3RAB9APPARGFFAR1HPGD | |
| SCHEMBL9143100 | 0.80 | HPGD (0.54) | HRH3RAB9APPARGFFAR1HPGD | |
| SCHEMBL8798105 | 0.78 | HRH3 (0.44) | HRH3RAB9APPARGFFAR1USP2 | |
| SCHEMBL8797389 | 0.77 | MGAM (0.55) | HRH3HPGDGAA | |
| SCHEMBL8797385 | 0.77 | MGAM (0.55) | HRH3HPGDGAA | |
| SCHEMBL8797062 | 0.76 | PPARG (0.36) | HRH3RAB9APPARGFFAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |