Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797373 | 0.89 | LPAR1 (0.44) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8797723 | 0.89 | LPAR1 (0.44) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8797534 | 0.89 | NLRP3 (0.39) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8798116 | 0.88 | TBXAS1 (0.39) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8797184 | 0.86 | LPAR1 (0.46) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8797272 | 0.85 | TP53 (0.45) | LPAR1KMT2ANLRP3LMNATBXA2R | |
| SCHEMBL8798136 | 0.85 | TP53 (0.42) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8797254 | 0.81 | NLRP3 (0.36) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8797400 | 0.80 | NLRP3 (0.39) | LPAR1KMT2ANLRP3LMNAMAPK1 | |
| SCHEMBL8798714 | 0.80 | TBXA2R (0.37) | LPAR1KMT2ANLRP3CYP3A4TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497201-B1 | Tricyclic compounds and intermediates thereof | KYOWA HAKKO KOGYO KK (JP) | 1997-01-15 | — | — | EP | claimed |