Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 5/20 | 0.32 |
| ▸ | HRH1 | P35367 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797429 | 0.96 | MAOB (0.35) | HRH3MAOBGRM5 | |
| SCHEMBL8796918 | 0.89 | HRH3 (0.38) | HRH3DRD2 | |
| SCHEMBL8797206 | 0.89 | HRH3 (0.38) | HRH3MAOBDRD2 | |
| SCHEMBL8798105 | 0.87 | HRH3 (0.44) | HRH3MAOB | |
| SCHEMBL8797248 | 0.87 | HRH3 (0.37) | HRH3HRH2HRH1MEN1DRD2 | |
| SCHEMBL8797269 | 0.86 | HRH3 (0.35) | HRH3 | |
| SCHEMBL8797588 | 0.84 | DRD2 (0.36) | HRH3MAOBMEN1GRM5DRD2 | |
| SCHEMBL8796797 | 0.84 | FFAR1 (0.39) | HRH3MAOB | |
| SCHEMBL8796841 | 0.84 | HRH3 (0.39) | HRH3MAOBMEN1 | |
| SCHEMBL8797138 | 0.84 | HRH3 (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |