Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797039 | 0.93 | KDM4E (0.34) | HRH3PPARGFFAR1 | |
| SCHEMBL8797248 | 0.89 | HRH3 (0.37) | HRH3 | |
| SCHEMBL8797138 | 0.88 | HRH3 (0.34) | HRH3PPARGFFAR1ESR1 | |
| SCHEMBL8797133 | 0.86 | HRH3 (0.34) | HRH3PPARGFFAR1 | |
| SCHEMBL8797688 | 0.86 | HRH3 (0.35) | HRH3PPARGFFAR1 | |
| SCHEMBL8797588 | 0.86 | DRD2 (0.36) | HRH3ESR1ESR2 | |
| SCHEMBL8796797 | 0.86 | FFAR1 (0.39) | HRH3PPARGFFAR1 | |
| SCHEMBL8797744 | 0.86 | HRH3 (0.35) | HRH3PPARGFFAR1ESR1ESR2 | |
| SCHEMBL8797429 | 0.86 | MAOB (0.35) | HRH3PPARGFFAR1 | |
| SCHEMBL8796803 | 0.86 | HTT (0.36) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |