Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796692 | 0.96 | HRH3 (0.40) | HRH3BCHEACHEUGCGMMP1 | |
| SCHEMBL8803024 | 0.86 | HRH3 (0.41) | HRH3RAB9AFFAR1NPC1 | |
| SCHEMBL8797295 | 0.85 | FFAR1 (0.49) | HRH3FFAR1TSHRMEN1ALDH1A1 | |
| SCHEMBL8796714 | 0.82 | ALDH1A1 (0.41) | HRH3RAB9AFFAR1MEN1ALDH1A1 | |
| SCHEMBL8796685 | 0.81 | HRH3 (0.49) | HRH3FFAR1TSHRMEN1ALDH1A1 | |
| SCHEMBL8796706 | 0.81 | HRH3 (0.38) | HRH3BCHEACHEFFAR1ALDH1A1 | |
| SCHEMBL8796905 | 0.76 | HRH3 (0.38) | HRH3BCHEACHEKCNH2 | |
| SCHEMBL8799698 | 0.76 | HRH3 (0.41) | HRH3FFAR1 | |
| SCHEMBL8796863 | 0.76 | HRH3 (0.35) | HRH3BCHEACHEFFAR1KCNH2 | |
| SCHEMBL8797065 | 0.75 | HRH3 (0.41) | HRH3RAB9AFFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |