Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796987 | 0.88 | HRH3 (0.39) | HRH3DRD2DRD3 | |
| SCHEMBL8796706 | 0.87 | HRH3 (0.38) | HRH3FFAR1PPARGROCK2 | |
| SCHEMBL8796714 | 0.86 | ALDH1A1 (0.41) | HRH3FFAR1PPARGGRM2 | |
| SCHEMBL8803024 | 0.86 | HRH3 (0.41) | HRH3FFAR1PPARG | |
| SCHEMBL8799688 | 0.85 | FFAR1 (0.51) | HRH3FFAR1PPARG | |
| SCHEMBL8796692 | 0.80 | HRH3 (0.40) | HRH3 | |
| SCHEMBL8797206 | 0.79 | HRH3 (0.38) | HRH3FFAR1PPARGROCK2DRD2 | |
| SCHEMBL8797303 | 0.76 | HRH3 (0.37) | HRH3FFAR1 | |
| SCHEMBL8797412 | 0.76 | FFAR1 (0.39) | HRH3FFAR1PPARGROCK2 | |
| SCHEMBL8796797 | 0.75 | FFAR1 (0.39) | HRH3FFAR1PPARGROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |