Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796714 | 0.91 | ALDH1A1 (0.41) | HRH3CHRM5FFAR1PPARGALDH1A1 | |
| SCHEMBL8803024 | 0.91 | HRH3 (0.41) | HRH3FFAR1PPARGMAOAMAOB | |
| SCHEMBL8799698 | 0.87 | HRH3 (0.41) | HRH3FFAR1PPARGROCK2 | |
| SCHEMBL8796987 | 0.84 | HRH3 (0.39) | HRH3ALDH1A1 | |
| SCHEMBL8796703 | 0.84 | FFAR1 (0.49) | HRH3FFAR1PPARGMAPT | |
| SCHEMBL8797303 | 0.81 | HRH3 (0.37) | HRH3FFAR1ALDH1A1LMNAMAPT | |
| SCHEMBL8797138 | 0.80 | HRH3 (0.34) | HRH3FFAR1PPARG | |
| SCHEMBL8796692 | 0.77 | HRH3 (0.40) | HRH3ALDH1A1MAPTBCHEACHE | |
| SCHEMBL8796918 | 0.76 | HRH3 (0.38) | HRH3 | |
| SCHEMBL8796710 | 0.75 | FFAR1 (0.48) | HRH3FFAR1PPARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |