Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 11/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797518 | 0.89 | METAP2 (0.35) | FFAR1METAP2METAP1TGFBR1KCNH2 | |
| SCHEMBL8798213 | 0.82 | MAPT (0.36) | METAP1KDM4EMEN1HTTKMT2A | |
| SCHEMBL9527675 | 0.81 | METAP2 (0.37) | FFAR1METAP2METAP1TGFBR1KCNH2 | |
| SCHEMBL8332841 | 0.81 | METAP2 (0.40) | METAP2METAP1TGFBR1MAPK13MAPK12 | |
| SCHEMBL8798384 | 0.81 | CBFB (0.37) | KCNH2GRM5 | |
| SCHEMBL8797575 | 0.80 | ABCB1 (0.34) | — | |
| SCHEMBL8797621 | 0.77 | BRD4 (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL8313790 | 0.77 | TGFBR1 (0.39) | METAP2METAP1TGFBR1MAPK13MAPK12 | |
| SCHEMBL8123176 | 0.76 | GRM5 (0.39) | METAP2METAP1TGFBR1MAPK13MAPK12 | |
| SCHEMBL8798410 | 0.71 | LRRK2 (0.34) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514942-B1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1997-03-05 | — | — | EP | disclosed |
| US-5493029-A | USEFUL IN TREATING ASTHMA AND HYPERTENSION | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-02-20 | — | — | US | disclosed |
| US-5300511-A | Spiro-benzopyran derivatives and useful for treating asthma and hypertension | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-04-05 | — | — | US | disclosed |
| EP-0514942-A1 | Novel benzopyran derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-11-25 | — | — | EP | disclosed |