Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | DHODH | Q02127 | 9/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502174 | 0.88 | L3MBTL1 (0.49) | ALDH1A1KDM4EDHODHKMT2AL3MBTL1 | |
| SCHEMBL7497000 | 0.86 | DHODH (0.56) | ALDH1A1KDM4EDHODHKMT2AL3MBTL1 | |
| SCHEMBL8800517 | 0.80 | KMT2A (0.67) | ALDH1A1KDM4EDHODHKMT2AL3MBTL1 | |
| SCHEMBL8604699 | 0.77 | DHODH (0.64) | ALDH1A1KDM4EDHODHHDAC6KMT2A | |
| SCHEMBL14398931 | 0.77 | DHODH (0.56) | ALDH1A1KDM4EDHODHKMT2AL3MBTL1 | |
| SCHEMBL18640758 | 0.76 | NPC1 (0.61) | ALDH1A1KDM4EDHODHKMT2AL3MBTL1 | |
| SCHEMBL18640720 | 0.76 | DHODH (0.65) | ALDH1A1KDM4EDHODHKMT2AHTT | |
| SCHEMBL504015 | 0.75 | ALB (0.61) | ALDH1A1KDM4EKMT2ALMNAGAA | |
| SCHEMBL29570483 | 0.75 | ALB (0.61) | ALDH1A1KDM4EKMT2ALMNAGAA | |
| SCHEMBL3820618 | 0.75 | HTT (0.66) | ALDH1A1KDM4EDHODHKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |