Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797407 | 0.88 | ALDH1A1 (0.52) | L3MBTL1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL7493834 | 0.81 | KMT2A (0.65) | L3MBTL1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL7572668 | 0.80 | KMT2A (0.50) | L3MBTL1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL8797276 | 0.80 | KMT2A (0.50) | L3MBTL1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL8801750 | 0.79 | USP2 (0.47) | L3MBTL1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL8797556 | 0.78 | CYP11B2 (0.58) | L3MBTL1KMT2AALDH1A1MAPTUSP2 | |
| SCHEMBL8798058 | 0.76 | ALDH1A1 (0.55) | L3MBTL1KMT2AHTTALDH1A1POLB | |
| SCHEMBL7570572 | 0.76 | NAMPT (0.55) | L3MBTL1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL3442002 | 0.76 | ALDH1A1 (0.63) | KMT2AALDH1A1ALOX15GAARAB9A | |
| SCHEMBL8798493 | 0.75 | USP2 (0.52) | L3MBTL1KMT2AHTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |