Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111527 | 0.98 | DPP7 (0.66) | DPP7SLC6A3SIGMAR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8843424 | 0.96 | DPP7 (0.64) | DPP7SLC6A3SIGMAR1KMT2AMEN1 | |
| SCHEMBL5133081 | 0.83 | HTT (0.56) | DPP7SIGMAR1KMT2AMEN1TDP1 | |
| SCHEMBL5756091 | 0.81 | DPP7 (1.00) | DPP7SLC6A3SIGMAR1KMT2AMEN1 | |
| SCHEMBL6203931 | 0.81 | SIGMAR1 (0.72) | DPP7SLC6A3SIGMAR1LTA4HACHE | |
| SCHEMBL18720377 | 0.80 | DPP7 (0.50) | DPP7SIGMAR1KMT2AMEN1TDP1 | |
| Hydrochloric Acid SCHEMBL5754930 | 0.79 | DPP7 (0.96) | DPP7SLC6A3SIGMAR1KMT2AMEN1 | |
| SCHEMBL8883456 | 0.79 | DPP7 (0.96) | DPP7SLC6A3SIGMAR1KMT2AMEN1 | |
| SCHEMBL14938163 | 0.79 | SIGMAR1 (0.70) | DPP7SLC6A3SIGMAR1LTA4HACHE | |
| Hydrochloric Acid SCHEMBL5759171 | 0.78 | DPP7 (0.93) | DPP7SLC6A3SIGMAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110879-B | Preparation method of sulcardine free alkali | 扬州中宝药业股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112110879-A | Preparation method of sulcardine free alkali | 扬州中宝药业股份有限公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-0796258-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES AS 5HT1 RECEPTOR AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017842-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES AS 5HT1 RECEPTOR AGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1996-06-13 | — | — | WO | disclosed |
| US-4400511-A | 2-Substituted octahydropyrrolo(1,2-A)-pyrazine-3-carboxylic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |