Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797839 | 0.86 | CSF1R (0.36) | ADORA2ACSF1RMAPTKDRAURKA | |
| SCHEMBL25706159 | 0.81 | MAPT (0.39) | MAPTPIN1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24818258 | 0.79 | ALDH1A1 (0.40) | MAPTPIN1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24817429 | 0.73 | GPR84 (0.38) | MAPTPIN1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL12469844 | 0.71 | ADORA2A (0.44) | ADORA2ACSF1RMAPTKDRAURKA | |
| SCHEMBL80142 | 0.70 | HDAC1 (0.48) | ADORA2ACSF1RMAPTALDH1A1 | |
| SCHEMBL21806653 | 0.69 | ADORA2A (0.43) | ADORA2ACSF1RMAPTKDRAURKA | |
| SCHEMBL28212557 | 0.68 | HDAC1 (0.47) | ADORA2ACSF1RMAPTKDRALDH1A1 | |
| SCHEMBL27515517 | 0.68 | HDAC1 (0.47) | ADORA2ACSF1RMAPTKDRALDH1A1 | |
| Fluoride SCHEMBL30394298 | 0.68 | HDAC1 (0.47) | ADORA2ACSF1RMAPTKDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597291-B1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO LTD (JP) | 1997-06-11 | — | — | EP | claimed |
| US-5321041-A | Antiallergens, antiinflammatory and anticaogulants | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-06-14 | — | — | US | claimed |
| EP-0597291-A1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-05-18 | — | — | EP | claimed |
| EP-0597291-B1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO LTD (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5321041-A | Antiallergens, antiinflammatory and anticaogulants | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-06-14 | — | — | US | disclosed |
| US-5321041-A | Antiallergens, antiinflammatory and anticaogulants | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-06-14 | — | — | US | disclosed |
| EP-0597291-A1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0597291-A1 | 2,3-diphenyl-5-pyrrolyl-furan derivatives, processes and intermediates for their preparation and their use as anti-inflammatory, and anti-allergic and platelet aggregation inhibiting agents | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |