SCHEMBL87978

SCHEMBL87978

NC1=C2C(=O)c3ccccc3C(=O)C2=CCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.38
ADORA2A P29274 2/20 0.38
FGR P09769 1/20 0.38
PIM1 P11309 1/20 0.38
CSNK1A1 P48729 1/20 0.38
CSNK1D P48730 1/20 0.38
DYRK1A Q13627 1/20 0.38
HIPK2 Q9H2X6 1/20 0.38
CSNK1G1 Q9HCP0 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CDC25B P30305 1/20 0.38
NPC1 O15118 6/20 0.37
RAB9A P51151 6/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
PTPRC P08575 4/20 0.37
MAPT P10636 4/20 0.37
POLB P06746 3/20 0.37
LMNA P02545 3/20 0.37
APAF1 O14727 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8718783 0.79 MEN1 (0.38) MAOAMEN1KMT2ACDC25BNPC1
SCHEMBL4800950 0.78 MEN1 (0.50) MAOAADORA2AFGRPIM1CSNK1A1
SCHEMBL4621390 0.74 CDC25B (0.55) MAOAADORA2AFGRPIM1CSNK1A1
SCHEMBL9267507 0.69 APAF1 (0.43) MAOAADORA2AFGRPIM1CSNK1A1
SCHEMBL24948978 0.69 HSP90AA1 (0.43) ADORA2AMEN1KMT2ACDC25BPTPRC
Quinizarin SCHEMBL29142553 0.67 MAPT (0.66) MAOAADORA2AFGRPIM1CSNK1A1
SCHEMBL14003716 0.66 CDC25B (0.73) MAOAADORA2AFGRPIM1CSNK1A1
SCHEMBL16745451 0.65 RAB9A (0.60) MAOAADORA2AFGRPIM1CSNK1A1
SCHEMBL14389753 0.65 PTPRC (0.52) MAOAMEN1KMT2ACDC25BNPC1
SCHEMBL11236776 0.64 APAF1 (0.42) MAOAMEN1KMT2ACDC25BNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016039960-A1 LASER REACTIVE WATER-BASED INKS MANUFACTURED FROM WATER-BASED MASTERBATCH CONCENTRATES SUN CHEMICAL CORPORATION (US) 2016-03-17 WO claimed
US-8506695-B2 Matrix of oligomer of tripropylene glycol diacrylate, melamine acrylate, amine functional polyester acrylate, hexanediol diacrylate, dendritic polyester-based acrylate, and/or bisphenol-A epoxy diacrylate with activator dissolved ; 4,4*-dihydroxydiphenyl sulfone color former; leuco dye; packages HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2013-08-13 US claimed
US-7575844-B2 Color forming composites capable of multi-colored imaging and associated systems and methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-08-18 US claimed
US-7501172-B2 Integrated recording and labeling with optical recording device HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-03-10 US claimed
EP-1264212-B1 ELEMENTS FOR FORMING PRINT-OUT IMAGES DU PONT (US) 2009-02-18 EP claimed
EP-1251400-B1 A photopolymerizable element for use as a flexographic printing plate and a process for preparing the plate from the element DU PONT (US) 2009-02-04 EP claimed
WO-2008134548-A1 COLOR FORMING COMPOSITES CAPABLE OF MULTI-COLORED IMAGING AND ASSOCIATED SYSTEMS AND METHODS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-11-06 WO claimed
US-20080268384-A1 Color forming composites capable of multi-colored imaging and associated systems and methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-10-30 US claimed
US-20080214392-A1 INKS FOR USE ON LIGHT-ACTIVATED IMAGING MEDIA GORE MAKARAND P 2008-09-04 US claimed
US-20080103042-A1 Matrix of oligomer of tripropylene glycol diacrylate, melamine acrylate, amine functional polyester acrylate, hexanediol diacrylate, dendritic polyester-based acrylate, and/or bisphenol-A epoxy diacrylate with activator dissolved ; 4,4*-dihydroxydiphenyl sulfone color former; leuco dye; packages HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-05-01 US claimed
EP-1264212-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. du Pont de Nemours and Company (US) 2002-12-11 EP claimed
EP-1251400-A2 A photopolymerizable element for use as a flexographic printing plate and a process for preparing the plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-10-23 EP claimed
US-20020146649-A1 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY 2002-10-10 US claimed
WO-2001067175-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-13 WO claimed
US-5744280-A MONOCHROME IMAGES;IMPROVED CONTRAST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-28 US claimed
EP-0828182-A1 Storage-stable photoimageable compositions with improved leuco dye E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-11 EP claimed
US-5055373-A Support with coating layer of microcapsules containing leuco dyes and photooxidizer and external reducing agent FUJI PHOTO FILM CO., LTD. (JP) 1991-10-08 US claimed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
US-4634657-A AND A LEEVCO DYE, MONOMERIC COMPOUND AND PHOTOINIATOR; IMPROVED PRINTOUT CAPABILITIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-06 US claimed
US-4090877-A COLOR PHOTOGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-23 US claimed