Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384396 | 0.72 | CYP3A4 (0.41) | MAOBTP53MAPTPTGS2PTGS1 | |
| SCHEMBL4198220 | 0.71 | SIGMAR1 (0.37) | HSP90AA1FGFR1MAPTPTGS2PTGS1 | |
| SCHEMBL87978 | 0.69 | MAOA (0.38) | MAOBTP53MAPTADORA2AS100A4 | |
| SCHEMBL7101602 | 0.67 | FGFR1 (0.57) | HSP90AA1HSP90AB1MAOBFGFR1SRC | |
| SCHEMBL8718783 | 0.66 | MEN1 (0.38) | HSP90AA1HSP90AB1MAOBTP53MAPT | |
| SCHEMBL11236776 | 0.66 | APAF1 (0.42) | HSP90AA1HSP90AB1TP53MAPTS100A4 | |
| SCHEMBL24531544 | 0.66 | PTPRC (0.40) | FGFR1FGFR2FGFR4FGFR3MAPT | |
| SCHEMBL21732765 | 0.65 | S100A4 (0.66) | MAOBFGFR1SRCFGFR2FGFR4 | |
| Ammonia Solution, Strong SCHEMBL27744473 | 0.65 | APAF1 (0.41) | HSP90AA1HSP90AB1TP53MAPTS100A4 | |
| SCHEMBL4621390 | 0.64 | CDC25B (0.55) | TP53MAPTADORA2AS100A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523834-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |