Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13553349 | 0.80 | GRM5 (0.38) | GRM5KDM4E | |
| SCHEMBL879790 | 0.79 | GRM5 (0.37) | GRM5KDM4E | |
| SCHEMBL849673 | 0.77 | GRM5 (0.37) | GRM5KDM4E | |
| SCHEMBL16302476 | 0.70 | KDM4E (0.39) | GRM5KDM4E | |
| SCHEMBL879789 | 0.67 | GRM5 (0.36) | GRM5KDM4E | |
| SCHEMBL12203987 | 0.62 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL4746141 | 0.60 | KMT2A (0.51) | KDM4E | |
| SCHEMBL21477233 | 0.60 | MAPT (0.46) | GRM5KDM4E | |
| SCHEMBL7983296 | 0.59 | RIPK1 (0.41) | GRM5KDM4E | |
| SCHEMBL17215263 | 0.58 | BRD4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |