Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040556 | 0.85 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL7838938 | 0.83 | CA1 (0.39) | ALDH1A1TDP1GAAMEN1KMT2A | |
| SCHEMBL8939785 | 0.77 | HTR1A (0.42) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL2778847 | 0.75 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL285182 | 0.75 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL16961397 | 0.74 | MCHR1 (0.38) | ALDH1A1L3MBTL1MAPTNPSR1CYP1A2 | |
| SCHEMBL1069301 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL1301200 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL2971848 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL160177 | 0.73 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1MAPTNPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777653-A1 | DIHYGROPYRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | PFIZER INC. (US) | 1997-06-11 | — | — | EP | claimed |