Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642548 | 0.90 | ALDH1A1 (0.43) | CALM1CA1CA2ABL1BCR | |
| SCHEMBL8797591 | 0.84 | ALOX5 (0.47) | ALOX5PTGS2ALOX15ALOX12CALM1 | |
| SCHEMBL30679916 | 0.84 | ALOX5 (0.47) | ALOX5PTGS2ALOX15ALOX12CALM1 | |
| SCHEMBL8797818 | 0.82 | ALOX5 (0.46) | ALOX5PTGS2ALOX15ALOX12CALM1 | |
| SCHEMBL28173580 | 0.81 | CA1 (0.37) | CALM1CA1CA2ABL1CYP3A4 | |
| SCHEMBL1119249 | 0.80 | ALOX5 (0.54) | ALOX5PTGS2ALOX15ALOX12CA1 | |
| SCHEMBL6827911 | 0.79 | ALDH1A1 (0.46) | CA2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL6443831 | 0.78 | ERN1 (0.42) | ALOX5PTGS2ALOX15ALOX12CALM1 | |
| SCHEMBL31488167 | 0.78 | CA2 (0.67) | PTGS2ALOX15CA1CA2CYP3A4 | |
| SCHEMBL957652 | 0.78 | CYP3A4 (0.40) | CYP3A4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542671-B1 | Substituted hydroquinone derivatives as intermediates of benzofuran derivatives | CIBA GEIGY AG (CH) | 1997-01-02 | — | — | EP | claimed |
| EP-0542671-A1 | Substituted hydroquinone derivatives as intermediates of benzofuran derivatives | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | claimed |
| US-5693807-A | Substituted hydroquinone derivatives | CIBA-GEIGY CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0542671-B1 | Substituted hydroquinone derivatives as intermediates of benzofuran derivatives | CIBA GEIGY AG (CH) | 1997-01-02 | — | — | EP | disclosed |
| US-5290939-A | Process for the manufacture of brofaromine and analogs thereof | CIBA-GEIGY CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| EP-0542671-A1 | Substituted hydroquinone derivatives as intermediates of benzofuran derivatives | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | disclosed |