Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 4/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483300 | 0.77 | CCR2 (0.54) | CA2MAOBCCR2AKR1B1CA12 | |
| SCHEMBL6737172 | 0.77 | CA2 (0.46) | CA2CCR2AKR1B1CA12CA1 | |
| SCHEMBL9063028 | 0.72 | CA2 (0.67) | CA2CCR2AKR1B1CA12CA1 | |
| SCHEMBL720789 | 0.72 | CA2 (0.67) | CA2CCR2AKR1B1CA12CA1 | |
| SCHEMBL7261695 | 0.72 | CA2 (0.51) | CA2CA12CA1CA9 | |
| SCHEMBL18224099 | 0.72 | CA2 (0.51) | CA2MAOBCA12CA1CA9 | |
| SCHEMBL18223598 | 0.72 | CA2 (0.45) | CA2CCR2CA12CA1CA9 | |
| SCHEMBL18233460 | 0.72 | CA2 (0.51) | CA2CCR2AKR1B1CA12CA1 | |
| SCHEMBL15843061 | 0.70 | MAOB (0.64) | CA2AHRMAOBKMOCA12 | |
| SCHEMBL8799877 | 0.69 | MEN1 (0.33) | KMOAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355827-B1 | Hydantoin derivatives | MOCHIDA PHARM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-RE35279-E | ALDOSE REDUCTASE INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5202339-A | Hypoglycemic, hypolipedemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5004751-A | Antidiabetic agents; aldoe reductase inhibitors | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-02 | — | — | US | disclosed |
| WO-1990002126-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355827-A2 | Hydantoin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |