SCHEMBL6737172

SCHEMBL6737172

O=S(=O)(Cl)c1cc2ccc(Cl)cc2o1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.46
CA12 O43570 2/20 0.45
CA9 Q16790 2/20 0.45
AKR1B1 P15121 1/20 0.43
CCR2 P41597 12/20 0.42
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4483300 0.85 CCR2 (0.54) CA2CA12CA9AKR1B1CCR2
SCHEMBL18223598 0.80 CA2 (0.45) CA2CA12CA9CCR2CA1
SCHEMBL8798152 0.77 CA2 (0.37) CA2CA12CA9AKR1B1CCR2
SCHEMBL720789 0.77 CA2 (0.67) CA2CA12CA9AKR1B1CCR2
SCHEMBL9063028 0.77 CA2 (0.67) CA2CA12CA9AKR1B1CCR2
SCHEMBL15881035 0.76 CA2 (0.72) CA2CA12CA9AKR1B1CA1
SCHEMBL18770111 0.76 CCR2 (0.47) CA2CA12CA9CCR2
Hydrochloric Acid SCHEMBL5734132 0.72 USP2 (0.55) CA12CA9AKR1B1
SCHEMBL15842521 0.69 MAOB (0.72) CA2CA12CA9CA1
SCHEMBL18770147 0.69 CCR2 (0.50) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1346994-A1 CHOLESTEROL BIOSYNTHESIS INHIBITORS CONTAINING AS THE ACTIVE INGREDIENT TRICYCLIC SPIRO COMPOUNDS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2003-09-24 EP disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 CA2 2790/4885CA12 3106/4885CA9 3719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.