Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 5/20 | 0.49 |
| ▸ | NOS1 | P29475 | 6/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PAH | P00439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2982031 | 0.81 | HPRT1 (0.53) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL1765839 | 0.81 | HPRT1 (0.41) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL10509301 | 0.72 | HPRT1 (0.50) | HPRT1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL2128394 | 0.71 | HPRT1 (0.49) | HPRT1NOS1PNP | |
| SCHEMBL9799100 | 0.70 | HPRT1 (0.48) | HPRT1NOS1NOS3NOS2PNP | |
| SCHEMBL10508430 | 0.70 | HPRT1 (0.48) | HPRT1MAPTPNP | |
| SCHEMBL9054339 | 0.70 | HPRT1 (0.78) | HPRT1PNP | |
| SCHEMBL9798192 | 0.70 | HPRT1 (0.50) | HPRT1NOS1NOS3NOS2PNP | |
| SCHEMBL10507662 | 0.70 | HPRT1 (0.50) | HPRT1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10737422 | 0.69 | HPRT1 (0.58) | HPRT1NOS1USP2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775142-A1 | SUBSTITUTED O6 -BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1997-05-28 | — | — | EP | claimed |