Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667990 | 0.80 | KIF11 (0.51) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25235287 | 0.76 | AKR1B10 (0.49) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5032627 | 0.75 | GRIN2D (0.60) | KMT2AALDH1A1ALOX12L3MBTL1KDM4E | |
| SCHEMBL13653068 | 0.75 | RARB (0.51) | MEN1KMT2ANR1H4MAPTRARB | |
| SCHEMBL3896659 | 0.75 | AKR1B10 (0.47) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3896652 | 0.75 | AKR1B10 (0.47) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3335783 | 0.75 | ALDH1A1 (0.69) | NPC1PPARGMEN1KMT2ANR1H4 | |
| SCHEMBL10742633 | 0.74 | CA12 (0.64) | PPARGMEN1KMT2ANR1H4PPARA | |
| SCHEMBL3240455 | 0.74 | CDC25B (0.50) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25935194 | 0.74 | PTGFR (0.52) | NPC1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763524-A1 | Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use | SANKYO COMPANY LIMITED (JP) | 1997-03-19 | — | — | EP | disclosed |