SCHEMBL9536404

SCHEMBL9536404

COc1ncc(Cl)c2nc(S(=O)(=O)Nc3c(Cl)cccc3Cl)nn12

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 13/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6244148 0.90 CCR4 (0.39) CCR4TSHR
SCHEMBL8848553 0.90 CCR4 (0.39) CCR4TSHR
SCHEMBL8556082 0.90 CCR4 (0.41) CCR4TSHR
SCHEMBL8901312 0.87 PTGS2 (0.34) CCR4TSHR
SCHEMBL8884295 0.84 CCR4 (0.35) CCR4TSHR
SCHEMBL9536181 0.82 CCR4 (0.42) CCR4TSHR
SCHEMBL8945421 0.81 SLC40A1 (0.37)
SCHEMBL9185284 0.80 CCR4 (0.51) CCR4
SCHEMBL9182478 0.80 CCR4 (0.47) CCR4
SCHEMBL8560163 0.80 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343752-B1 Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates DOWELANCO (US) 1993-12-01 EP claimed