Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019189 | 0.66 | MEN1 (0.44) | ALDH1A1TP53PTGS1PTGS2NPC1 | |
| SCHEMBL3840884 | 0.63 | PDE3B (0.50) | KDM4EALDH1A1HPGDPDK2GAA | |
| SCHEMBL21945443 | 0.63 | PTGDR2 (0.51) | PTGDR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9812827 | 0.60 | ALOX5 (0.58) | ALDH1A1HPGDPTGS1PTGS2NPC1 | |
| SCHEMBL9547529 | 0.60 | PTGS2 (0.42) | KDM4EALDH1A1HPGDTP53GAA | |
| SCHEMBL2296728 | 0.60 | PTGDR2 (0.48) | PTGDR2HTTNPC1RAB9AMAPT | |
| SCHEMBL9015117 | 0.60 | GCGR (0.50) | KDM4EALDH1A1HPGDGAAHTT | |
| SCHEMBL24909729 | 0.59 | KDM4E (0.43) | KDM4EALDH1A1HPGDGAAHTT | |
| SCHEMBL10088967 | 0.59 | S1PR1 (0.42) | GAAPTGDR2PTGS2 | |
| SCHEMBL4936635 | 0.59 | GAA (0.66) | KDM4EALDH1A1HPGDTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5281719-A | Reacting a methyl N-((trimethylsilyl)methyl)thiobenzimidate with 2,3-dichloro-hexafluorobutene to give a 2-aryl-3,4-bis-(trifluoromethyl)pyrrole and reacting this with a halogenating compound | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5229524-A | Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | disclosed |