Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799594 | 0.71 | PTGS2 (0.35) | PTGS2PTGS1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9316723 | 0.66 | PTGS1 (0.38) | PTGS2PTGS1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9316197 | 0.66 | AR (0.51) | PTGS2PTGS1KDM4EALDH1A1HTT | |
| SCHEMBL3840884 | 0.63 | PDE3B (0.50) | CYP1A2CYP2C19TSHRKDM4EALDH1A1 | |
| SCHEMBL9019189 | 0.63 | MEN1 (0.44) | PTGS2PTGS1TSHRALDH1A1MEN1 | |
| SCHEMBL4587739 | 0.61 | NOTUM (0.45) | KDM4EALDH1A1HTTHPGDMEN1 | |
| SCHEMBL8798669 | 0.60 | KDM4E (0.38) | PTGS2PTGS1NPSR1KDM4EALDH1A1 | |
| SCHEMBL17437283 | 0.60 | PTGS2 (0.65) | PTGS2PTGS1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL29684047 | 0.60 | KDM4E (0.39) | PTGS2PTGS1CYP1A2CYP2C19KDM4E | |
| SCHEMBL8798565 | 0.60 | KDM4E (0.43) | PTGS2PTGS1CYP1A2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229524-A | Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-07-20 | — | — | US | disclosed |