SCHEMBL879877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL70173	0.83	CYP4F2 (0.83)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5
	SCHEMBL5663990	0.82	CYP4A11 (0.91)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5
	SCHEMBL10606812	0.82	CYP4A11 (0.75)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5
	SCHEMBL1792728	0.82	CYP4A11 (0.75)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5
	SCHEMBL850937	0.82	FOLH1 (0.53)	MRGPRX4FOLH1ALDH1A1HIF1A
	SCHEMBL10144968	0.82	LOXL2 (0.64)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5
	SCHEMBL880015	0.82	CYP4A11 (0.66)	CYP4F2CYP4A11LOXL2ALDH1A1HPGD
	SCHEMBL10291095	0.81	CYP4F2 (0.67)	CYP4F2CYP4A11ALDH1A1HPGDMAPT
	SCHEMBL18540811	0.81	CYP4A11 (1.00)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5
	SCHEMBL8921794	0.81	CYP4A11 (0.73)	CYP4F2CYP4A11LOXL2MRGPRX4SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.