Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799536 | 0.80 | CA1 (0.70) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL10474248 | 0.78 | PSMB8 (0.57) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL6985918 | 0.74 | SMN1; SMN2 (0.58) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL29257742 | 0.73 | PSMB8 (0.54) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL8799542 | 0.72 | CA1 (0.55) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL10474769 | 0.72 | PSMB8 (0.64) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL8229512 | 0.72 | PSMB8 (0.64) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL31452859 | 0.71 | TARS1 (0.61) | CA1CA2ALDH1A1PSMB8PSMB5 | |
| SCHEMBL8973664 | 0.70 | ATM (0.37) | ALDH1A1SMN1; SMN2MEN1LMNAHTT | |
| SCHEMBL31463118 | 0.70 | PSMB8 (0.70) | CA1CA2ALDH1A1PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355827-B1 | Hydantoin derivatives | MOCHIDA PHARM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| WO-1990002126-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-08 | — | — | WO | disclosed |
| EP-0355827-A2 | Hydantoin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |