Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | TMPRSS11D | O60235 | 10/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.46 |
| ▸ | PLG | P00747 | 5/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597124 | 1.00 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1TMPRSS11DITGB3 | |
| Sarcosine SCHEMBL8800822 | 0.92 | TMPRSS11D (0.43) | SLC1A3SLC1A2SLC1A1TMPRSS11DITGB3 | |
| SCHEMBL18419482 | 0.88 | F10 (0.47) | TMPRSS11DITGB3ITGA2BF2F10 | |
| Arginine SCHEMBL7359381 | 0.87 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1TMPRSS11DITGB3 | |
| SCHEMBL7125358 | 0.85 | NPY4R (0.51) | TMPRSS11DF2F10PLG | |
| SCHEMBL8806578 | 0.82 | F10 (0.43) | TMPRSS11DITGB3ITGA2BF2F10 | |
| SCHEMBL3448321 | 0.82 | MMP9 (0.58) | ITGB3ITGA2BMMP2MMP9MMP1 | |
| SCHEMBL3448325 | 0.82 | MMP9 (0.58) | ITGB3ITGA2BMMP2MMP9MMP1 | |
| SCHEMBL30309011 | 0.81 | ITGB3 (0.65) | SLC1A3SLC1A2SLC1A1TMPRSS11DITGB3 | |
| SCHEMBL12044849 | 0.80 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1TMPRSS11DITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801654-A1 | N-SUBSTITUTED GLYCINE DERIVATIVES AS INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1997-10-22 | — | — | EP | disclosed |