Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30355296 | 0.85 | FOLH1 (0.44) | CTSKTGM2CA2 | |
| SCHEMBL8572501 | 0.84 | FOLH1 (0.50) | TGM2CA2 | |
| SCHEMBL8572497 | 0.84 | FOLH1 (0.50) | TGM2CA2 | |
| SCHEMBL11206875 | 0.82 | FOLH1 (0.46) | TGM2SIRT2SIRT1 | |
| Hydrochloric Acid SCHEMBL22283120 | 0.82 | FOLH1 (0.49) | TGM2CA2 | |
| SCHEMBL9832042 | 0.82 | NOD1 (0.49) | CTSKCTSSCTSLNOD1TGM2 | |
| SCHEMBL9832048 | 0.82 | NOD1 (0.49) | CTSKCTSSCTSLNOD1TGM2 | |
| SCHEMBL16867534 | 0.81 | FOLH1 (0.53) | — | |
| SCHEMBL9830456 | 0.81 | NOD1 (0.47) | CTSKCTSSCTSLNOD1TGM2 | |
| SCHEMBL9830451 | 0.81 | NOD1 (0.47) | CTSKCTSSCTSLNOD1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650430-A | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO COMPANY, LIMITED (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0460950-B1 | Radicicol derivatives, their preparation and their anti-tumour activity | SANKYO CO (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5597846-A | ESTERS OF RADICICOL | SANKYO COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |