Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830456 | 1.00 | NOD1 (0.47) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL7382637 | 0.93 | NOD1 (0.48) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL1077922 | 0.93 | NOD1 (0.48) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL3625936 | 0.88 | NOD1 (0.50) | NOD1TGM2SIRT2SIRT1 | |
| SCHEMBL9832048 | 0.88 | NOD1 (0.49) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL9832042 | 0.88 | NOD1 (0.49) | NOD1CTSSCTSLCTSKTGM2 | |
| SCHEMBL29233084 | 0.87 | FOLH1 (0.51) | NOD1TGM2SIRT2SIRT1CA2 | |
| SCHEMBL29233086 | 0.87 | FOLH1 (0.51) | NOD1TGM2SIRT2SIRT1CA2 | |
| SCHEMBL3629433 | 0.87 | NOD1 (0.53) | NOD1SIRT2SIRT1ACHE | |
| SCHEMBL8973585 | 0.87 | NOD1 (0.55) | NOD1SIRT2SIRT1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |