Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798911 | 0.86 | LTB4R (0.67) | LTB4RLTB4R2 | |
| SCHEMBL8800121 | 0.85 | LTB4R (0.55) | LTB4RLTB4R2 | |
| SCHEMBL8799274 | 0.84 | LTB4R (0.61) | LTB4R | |
| SCHEMBL8987111 | 0.81 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8799165 | 0.80 | LTB4R (0.65) | LTB4R | |
| SCHEMBL8799511 | 0.79 | LTB4R (0.55) | LTB4RLTB4R2 | |
| SCHEMBL9119163 | 0.79 | PPARG (0.43) | — | |
| SCHEMBL8799160 | 0.77 | LTB4R (0.71) | LTB4RLTB4R2 | |
| SCHEMBL6757526 | 0.77 | LTB4R (0.62) | LTB4R | |
| SCHEMBL8799505 | 0.77 | ITGB3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755381-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028386-A1 | SUBSTITUTED PYRIDINE LEUKOTRIENE B4 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-26 | — | — | WO | disclosed |