Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799924 | 0.87 | CYP1A2 (0.40) | MAPK1LTA4HKMT2ACNR1TSHR | |
| SCHEMBL8798762 | 0.84 | LTA4H (0.41) | MAPK1SMN1; SMN2GRM2LTA4HKMT2A | |
| SCHEMBL8798260 | 0.83 | LTA4H (0.38) | MAPK1SMN1; SMN2LTA4HKMT2ACYP3A4 | |
| SCHEMBL8799637 | 0.78 | CYP3A4 (0.49) | MAPK1SMN1; SMN2KMT2ACYP3A4 | |
| SCHEMBL8798842 | 0.78 | DPP4 (0.40) | MAPK1SMN1; SMN2GRM2LTA4HKMT2A | |
| SCHEMBL8799769 | 0.77 | LTA4H (0.41) | MAPK1LTA4HKMT2ATSHRABCB11 | |
| SCHEMBL8799648 | 0.76 | MAPK1 (0.36) | MAPK1SMN1; SMN2CCNCCDK8GRM2 | |
| SCHEMBL8800040 | 0.75 | LTA4H (0.42) | MAPK1SMN1; SMN2LTA4HKMT2ATSHR | |
| SCHEMBL8633545 | 0.75 | SLC7A5 (0.43) | SMN1; SMN2LTA4HKMT2ATSHRCYP1A2 | |
| SCHEMBL1969926 | 0.74 | PPARA (0.56) | MAPK1SMN1; SMN2CCNCCDK8GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |