Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADA | P00813 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798260 | 0.91 | LTA4H (0.38) | LTA4HCYP3A4GPR119MAPK1SMN1; SMN2 | |
| SCHEMBL8799769 | 0.88 | LTA4H (0.41) | LTA4HCYP3A4GPR119MAPK1ALDH1A1 | |
| SCHEMBL8329546 | 0.87 | LTA4H (0.52) | LTA4HSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8799646 | 0.84 | MAPK1 (0.37) | LTA4HCYP3A4MAPK1SMN1; SMN2GRM2 | |
| SCHEMBL8798842 | 0.82 | DPP4 (0.40) | LTA4HCYP3A4GPR119MAPK1SMN1; SMN2 | |
| SCHEMBL8800040 | 0.82 | LTA4H (0.42) | LTA4HSLC1A5MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8803290 | 0.80 | LTA4H (0.46) | LTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL8798766 | 0.79 | CYP3A4 (0.37) | CYP3A4GPR119SLC1A5MAPK1SMN1; SMN2 | |
| SCHEMBL8798754 | 0.79 | CYP3A4 (0.57) | CYP3A4ALDH1A1KMT2AKDM4E | |
| SCHEMBL8799063 | 0.78 | LTA4H (0.45) | LTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |