Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329546 | 0.85 | LTA4H (0.52) | LTA4HSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL8799769 | 0.83 | LTA4H (0.41) | LTA4HCYP1A2LMNAALDH1A1HPGD | |
| SCHEMBL8798762 | 0.82 | LTA4H (0.41) | LTA4HCYP1A2SLC1A5SMN1; SMN2ALDH1A1 | |
| SCHEMBL8803290 | 0.80 | LTA4H (0.46) | LTA4HSMN1; SMN2ALDH1A1CTSSCTSK | |
| SCHEMBL8800029 | 0.78 | KEAP1 (0.42) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL8800048 | 0.78 | PGR (0.35) | LTA4HCYP1A2SLC1A5PGRADORA3 | |
| SCHEMBL8799063 | 0.78 | LTA4H (0.45) | LTA4HSMN1; SMN2LMNACTSSCTSK | |
| SCHEMBL8633545 | 0.77 | SLC7A5 (0.43) | LTA4HCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8798260 | 0.77 | LTA4H (0.38) | LTA4HSMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL8799924 | 0.76 | CYP1A2 (0.40) | LTA4HCYP1A2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |