Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563298 | 0.87 | NMT1 (0.33) | TSHR | |
| SCHEMBL8799981 | 0.78 | SLC22A12 (0.39) | TSHR | |
| SCHEMBL8798497 | 0.77 | TSHR (0.37) | TSHRPOLB | |
| SCHEMBL8556221 | 0.75 | TRPV4 (0.32) | — | |
| SCHEMBL910148 | 0.73 | TSHR (0.36) | TSHR | |
| SCHEMBL7852586 | 0.72 | CCR4 (0.36) | TSHR | |
| SCHEMBL8901664 | 0.69 | SMN1; SMN2 (0.39) | TSHR | |
| SCHEMBL9066675 | 0.69 | ACLY (0.38) | TSHR | |
| SCHEMBL8327069 | 0.68 | SMN1; SMN2 (0.34) | TSHR | |
| SCHEMBL8136597 | 0.68 | MEN1 (0.36) | TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537423-B1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0537423-A1 | N-pyrazolyl-1,2,4-triazolo(1,5-c)pyrimidine-2-sulfonamide herbicides | DowElanco (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5201938-A | N-pyrazolyl-1,2,4-triazolo[1,5-c]pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1993-04-13 | — | — | US | disclosed |