Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066675 | 0.92 | ACLY (0.38) | SMN1; SMN2MAPK1TSHRKMT2AGAA | |
| SCHEMBL8901668 | 0.92 | MAPT (0.35) | SMN1; SMN2ALDH1A1MAPK1LMNATSHR | |
| SCHEMBL8902858 | 0.91 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPK1LMNATSHRKMT2A | |
| SCHEMBL8113251 | 0.85 | LMNA (0.37) | SMN1; SMN2ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL8113240 | 0.82 | LMNA (0.36) | SMN1; SMN2ALDH1A1KDM4EMAPK1LMNA | |
| SCHEMBL910274 | 0.80 | GAA (0.42) | SMN1; SMN2MAPK1TSHRKMT2AGAA | |
| SCHEMBL9641243 | 0.80 | SLC40A1 (0.37) | ALDH1A1MAPK1LMNATSHRKMT2A | |
| SCHEMBL7074184 | 0.78 | TSHR (0.34) | SMN1; SMN2MAPK1TSHRKMT2AGAA | |
| SCHEMBL64266 | 0.77 | CA2 (0.34) | ALDH1A1MAPK1LMNATSHRKMT2A | |
| SCHEMBL30416435 | 0.77 | CA2 (0.34) | ALDH1A1MAPK1LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | claimed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |