Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570485 | 0.80 | GPR84 (0.48) | TAAR1HRH3MAPTHSD17B10MEN1 | |
| SCHEMBL14678488 | 0.77 | MGLL (0.52) | TAAR1HRH3MAPTHSD17B10MEN1 | |
| SCHEMBL10928551 | 0.76 | MAPT (0.46) | TAAR1HRH3MAPTHSD17B10MEN1 | |
| SCHEMBL2030841 | 0.75 | TAAR1 (0.71) | TAAR1HRH3ALDH1A1ADRA2AADRA2B | |
| SCHEMBL6237841 | 0.74 | HDAC1 (0.47) | TAAR1HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL2398501 | 0.74 | GLA (0.52) | MAPTHSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL3615427 | 0.73 | TAAR1 (0.52) | TAAR1HRH3ALDH1A1ADRA2AADRA2B | |
| SCHEMBL11522780 | 0.73 | TAAR1 (0.40) | TAAR1HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL8563268 | 0.73 | HRH3 (0.47) | TAAR1HRH3ALDH1A1 | |
| SCHEMBL10159010 | 0.73 | MAPT (0.56) | TAAR1HRH3MAPTHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |