Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799962 | 0.80 | TAAR1 (0.50) | CNOT7GAATAAR1HRH3MEN1 | |
| SCHEMBL5426939 | 0.75 | PDE2A (0.46) | CNOT7MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2774914 | 0.73 | ALDH1A1 (0.47) | CNOT7PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28562224 | 0.73 | KMT2A (0.60) | GAAMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL21493552 | 0.71 | CNOT7 (0.53) | GPR84CNOT7TAAR1HRH3MAPT | |
| SCHEMBL14678488 | 0.70 | MGLL (0.52) | CNOT7TAAR1HRH3MEN1KMT2A | |
| SCHEMBL8340428 | 0.70 | GAA (0.41) | CNOT7GAATAAR1HRH3HSD17B10 | |
| SCHEMBL30693612 | 0.70 | CNOT7 (0.43) | GPR84CNOT7HCAR2TAAR1HRH3 | |
| SCHEMBL10928551 | 0.69 | MAPT (0.46) | CNOT7GAATAAR1HRH3MEN1 | |
| SCHEMBL2030841 | 0.69 | TAAR1 (0.71) | TAAR1HRH3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |