Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974251 | 0.93 | GRIN1 (0.38) | GRIN1GRIN2BIDO1S1PR3 | |
| SCHEMBL6974146 | 0.90 | ALDH1A1 (0.36) | S1PR3NOX4 | |
| SCHEMBL8800346 | 0.89 | MEN1 (0.32) | GNRHR | |
| SCHEMBL8801330 | 0.89 | KDM4E (0.38) | S1PR3NOX4 | |
| SCHEMBL8801745 | 0.86 | ALDH1A1 (0.40) | GRIN1GRIN2B | |
| SCHEMBL6969897 | 0.86 | GRIN1 (0.38) | GRIN1GRIN2BIDO1S1PR3NOX4 | |
| SCHEMBL7079752 | 0.84 | GRIN1 (0.37) | GRIN1GRIN2BIDO1S1PR3NOX4 | |
| SCHEMBL7080221 | 0.83 | GNRHR (0.37) | GNRHR | |
| SCHEMBL8799639 | 0.83 | GRIN1 (0.35) | GRIN1GRIN2B | |
| SCHEMBL6961698 | 0.83 | S1PR3 (0.38) | S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |