Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974146 | 0.93 | ALDH1A1 (0.36) | ALDH1A1TP53TDP1GABRA5GABRA1 | |
| SCHEMBL8801551 | 0.91 | TDP1 (0.36) | ALDH1A1LMNATP53TDP1KMT2A | |
| SCHEMBL6974251 | 0.90 | GRIN1 (0.38) | ALDH1A1LMNAGRIN1GRIN2BPKM | |
| SCHEMBL8801330 | 0.89 | KDM4E (0.38) | ALDH1A1LMNA | |
| SCHEMBL7080221 | 0.87 | GNRHR (0.37) | ALDH1A1LMNAKMT2A | |
| SCHEMBL6971953 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNATP53GRIN1GRIN2B | |
| SCHEMBL8800166 | 0.86 | GRIN1 (0.37) | GRIN1GRIN2B | |
| SCHEMBL6967425 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNATP53GRIN1GRIN2B | |
| SCHEMBL8802789 | 0.85 | TP53 (0.37) | ALDH1A1LMNATP53TDP1NPC1 | |
| SCHEMBL7086183 | 0.84 | TP53 (0.35) | ALDH1A1TP53GRIN1GRIN2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |