Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 8/20 | 0.42 |
| ▸ | CCKAR | P32238 | 3/20 | 0.42 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800222 | 0.90 | FNTA (0.46) | FNTAFNTBCCKBRCCKAROXTR | |
| SCHEMBL8801821 | 0.82 | FNTA (0.48) | FNTAFNTBCCKBRCCKAROXTR | |
| SCHEMBL8800784 | 0.82 | CCKBR (0.46) | CCKBRCCKAROXTRKCNH2SENP1 | |
| SCHEMBL8667954 | 0.82 | CCKBR (0.48) | FNTAFNTBCCKBRCCKARKCNH2 | |
| SCHEMBL8674133 | 0.82 | CCKBR (0.48) | FNTAFNTBCCKBRCCKARKCNH2 | |
| SCHEMBL8800789 | 0.81 | FNTA (0.51) | FNTAFNTBCCKBRCCKAROXTR | |
| SCHEMBL8801804 | 0.81 | FNTA (0.54) | FNTAFNTBCCKBRCCKAROXTR | |
| SCHEMBL8800732 | 0.80 | FNTA (0.50) | FNTAFNTBCCKBRCCKAROXTR | |
| SCHEMBL8802052 | 0.80 | FNTA (0.51) | FNTAFNTBCCKBRCCKAROXTR | |
| SCHEMBL8667998 | 0.80 | FNTA (0.42) | FNTAFNTBCCKBRCCKARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | claimed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |