Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.46 |
| ▸ | CCKAR | P32238 | 3/20 | 0.45 |
| ▸ | OXTR | P30559 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800232 | 0.88 | OXTR (0.49) | CCKBRCCKAROXTRKCNH2 | |
| SCHEMBL8800767 | 0.86 | CCKBR (0.44) | CCKBRCCKAROXTR | |
| SCHEMBL8801839 | 0.83 | CCKBR (0.50) | CCKBRCCKAROXTR | |
| SCHEMBL8800775 | 0.82 | FNTA (0.43) | CCKBRCCKAROXTRKCNH2SENP1 | |
| SCHEMBL8801061 | 0.79 | FNTA (0.46) | CCKBRCCKAROXTRKCNH2 | |
| SCHEMBL8668005 | 0.78 | CCKBR (0.48) | CCKBROXTRKCNH2SENP1 | |
| SCHEMBL9435434 | 0.76 | FNTA (0.43) | CCKBRCCKAROXTRKCNH2 | |
| SCHEMBL8801333 | 0.75 | FNTA (0.52) | CCKBRCCKAROXTR | |
| SCHEMBL8801632 | 0.74 | CCKBR (0.40) | CCKBRCCKARKCNH2SENP1 | |
| SCHEMBL8674221 | 0.74 | CCKBR (0.51) | CCKBRCCKAROXTRKCNH2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | claimed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |