Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.48 |
| ▸ | CCKAR | P32238 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667954 | 1.00 | CCKBR (0.48) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8669315 | 0.93 | CCKBR (0.48) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8676596 | 0.92 | CCKBR (0.48) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8669230 | 0.90 | HTR2B (0.45) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8674155 | 0.87 | CCKBR (0.47) | CCKBRCCKARHDAC3HDAC1HDAC6 | |
| SCHEMBL8670033 | 0.87 | CCKBR (0.47) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8676603 | 0.86 | CCKBR (0.48) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8800936 | 0.86 | CCKBR (0.44) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8800222 | 0.85 | FNTA (0.46) | CCKBRCCKARFNTAFNTBKCNH2 | |
| SCHEMBL8674533 | 0.85 | CCKBR (0.49) | CCKBRCCKARKCNH2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |