SCHEMBL8800792

SCHEMBL8800792

CCCCc1nc(Cl)[c]n1Cc1ccc(-c2ccccc2)c(-c2nnn[nH]2)c1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 5/20 0.41
AGTR2 P50052 5/20 0.41
GP6 Q9HCN6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8799310 0.91 AGTR1 (0.47) AGTR1AGTR2GP6
SCHEMBL1457700 0.81 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL8741226 0.81 AGTR1 (0.54) AGTR1AGTR2
Potassium SCHEMBL8071014 0.80 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL8071013 0.80 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL3427175 0.80 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL9443002 0.80 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL8172767 0.80 GP6 (0.63) AGTR1AGTR2GP6
SCHEMBL27360016 0.79 PPARG (0.51) AGTR1AGTR2
SCHEMBL9402382 0.78 AGTR1 (0.44) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763033-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-03-19 EP claimed
WO-1995032198-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-11-30 WO claimed
EP-0763033-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-03-19 EP disclosed
WO-1995032198-A1 IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-11-30 WO disclosed