Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.47 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800792 | 0.91 | AGTR1 (0.41) | AGTR1AGTR2GP6 | |
| SCHEMBL8105649 | 0.82 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL29382524 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL15944209 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL940 | 0.81 | GP6 (0.56) | AGTR1AGTR2GP6ABCC4ABCB11 | |
| SCHEMBL3347428 | 0.81 | GP6 (0.54) | AGTR1AGTR2GP6ABCC4ABCB11 | |
| SCHEMBL3347424 | 0.80 | GP6 (0.53) | AGTR1AGTR2GP6ABCC4ABCB11 | |
| SCHEMBL13755335 | 0.80 | AGTR1 (0.58) | AGTR1AGTR2GP6ABCC4ABCB11 | |
| SCHEMBL6953051 | 0.80 | HSD11B1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9031100 | 0.80 | AGTR1 (0.72) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763033-A1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-03-19 | — | — | EP | claimed |
| WO-1995032198-A1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-11-30 | — | — | WO | claimed |
| EP-0763033-A1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032198-A1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-11-30 | — | — | WO | disclosed |